this post was submitted on 14 Mar 2025
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Science Memes

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[–] psoul@lemmy.world 39 points 3 days ago (4 children)

Can I get a T shirt that says “I have Dunning-Krueger and your Phd looks cute”? I just have a lot of BS to share and I don’t want to be sorry about it.

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[–] Zzyzx@lemmy.blahaj.zone 32 points 3 days ago (2 children)

You know how a bunch of villains are Dr. So-and-So? I bet it's dealing with morons talking about your area of expertise that leads to one's villain era.

[–] Kolanaki@pawb.social 11 points 3 days ago

"That's doctor Evil. I didn't spend 8 years in evil medical school to be called mister, thank you very much."

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[–] LongLive@lemmy.world 13 points 2 days ago* (last edited 1 day ago) (3 children)
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[–] OsrsNeedsF2P@lemmy.ml 26 points 3 days ago (19 children)

Can someone explain to me how some XX people become cis male?

[–] ragebutt@lemmy.dbzer0.com 41 points 3 days ago

De La Chappell syndrome, congenital adrenal hyperplasia, androgen exposure in utero, ovotesticular disorder of of sex development all result in a person with cis male characteristics and in some cases cis male typical genitalia despite having xx chromosomes

[–] forrgott@lemm.ee 40 points 3 days ago

Gene expression is not as straightforward as people think. All sorts of weird shit can happen, and that's not even including gene mutations.

[–] evasive_chimpanzee@lemmy.world 26 points 3 days ago* (last edited 3 days ago) (1 children)

https://static.scientificamerican.com/sciam/assets/File/Pitch_sketch_final.png?w=2000

This is the best resource I've seen to show things relatively simply.

The TL;DR is that a whole "Y" chromosome isn't exactly responsible for "maleness", the SRY gene is. It's normally on the Y chromosome, but mutations can occur placing that gene onto the X chromosome. Inversely, someone could inherit a Y chromosome without that gene, in which case they would develop with female traits.

It's not considered trans because someone with 46XX plus the SRY gene would develop male genitalia, be identified as male at birth, and likely identify themselves as male. For some types of these conditions, there are plenty of people walking around with no clue that their chromosomes don't match their gender.

Disclaimer: I'm not a geneticist, so i could have explained something a little off.

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[–] OmnipotentEntity@beehaw.org 22 points 3 days ago* (last edited 3 days ago)

I googled it for you.

https://en.wikipedia.org/wiki/XX_male_syndrome

In 90 percent of these individuals, the syndrome is caused by the Y chromosome's SRY gene, which triggers male reproductive development, being atypically included in the crossing over of genetic information that takes place between the pseudoautosomal regions of the X and Y chromosomes during meiosis in the father.[2][7] When the X with the SRY gene combines with a normal X from the mother during fertilization, the result is an XX genetic male. Less common are SRY-negative individuals, those who are genetically females, which can be caused by a mutation in an autosomal or X chromosomal gene.[2] The masculinization of XX males is variable.

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[–] alykanas@slrpnk.net 19 points 3 days ago* (last edited 3 days ago) (10 children)

How do you know if someone has a PhD.?

They tell you

Never not true

[–] papertowels@mander.xyz 34 points 3 days ago

I mean yeah, if you spent 5 years of your life pushing the edge of human understanding on a subject, and a shithead tells you to do the science on your research subject, it's relevant lol

Tbf, they kinda earned the right to brag.

[–] Franklin@lemmy.ca 32 points 3 days ago

True, but I do think it was warranted in this case.

[–] thevoidzero@lemmy.world 26 points 3 days ago (1 children)

Well you don't know people with PhD that don't tell you they have one

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[–] dQw4w9WgXcQ@lemm.ee 27 points 3 days ago

This is putting confirmation bias to the extreme.

[–] drtaco@lemmy.dbzer0.com 12 points 3 days ago (3 children)

Sometimes they don't tell you and just quietly update all of their usernames...

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[–] rambling_lunatic@sh.itjust.works 15 points 3 days ago (1 children)

I'm a bit uninformed on this; it seems fascinating. Do these things happen due to something unusual during the growth of a fetus? What's the name for this phenomenon?

[–] dondelelcaro@lemmy.world 35 points 3 days ago (6 children)

There's a bunch of them, but one more common example is Androgen Insensitivity Syndrome.

It's also possible to have a non-functional SRY (XY but female), or to be XX with an SRY translocation (XX but male).

Biology is complicated: pretty much anyone who says it only happens one way or is really simple is wrong.

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[–] 4oreman@lemy.lol 19 points 3 days ago (7 children)
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