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If we MUST eat a entire bag of Oreos.
Which scenario is better?
Yeah, but it's also not meant to process a giant package of processed fats, levels of sugar we haven't had time to adapt to, or the colorant used that is known to irritate the bowel.
Which is why folks that go on a cookie spree like that end up constipated or loose and crampy. Which, yeah there's some folks that would be able to take a giant hit of junk like that without noticing it, but I've had to clean up the mess left by Oreos when patients would go crazy on them for one reason or another (often dementia, sadly).
No, it isn't going to kill you, or send you to the hospital purely by the digestive side of things, but it can fuck up your day lol.
Also, you're misrepresenting not only what I said, but what the digestive tract is "built" for. It doesn't actually benefit from irregularity of diet. It can handle it, but eating a fairly stable, non irritating diet keeps both the gut flora and the associated hormonal products produced in the intestines at a reliable operation. The more you disturb the system, the less stable the system. When it comes to gut flora and serotonin production in the gut, high sugar intake disrupts in a way that can have lingering effects; anything from a day to a week.
Don't mistake the difference between a varied healthy diet and shoving irritants down the pipes. They aren't the same thing.