What if everything you've been told about pbf diets and heart disease is wrong? In this exclusive interview, I sit down with Dr. Ankur Verma, an emergency medical doctor in India who's compiling one of the largest observational datasets on diet and metabolic illness (over 10,000 real patients and counting). What he's seeing is incredibly alarming. From rampant B12 deficiencies and soaring homocysteine levels to heart attacks in so-called "healthy" pbf eaters, this conversation pulls back the curtain on what’s actually driving India's exploding diabetes and cardiovascular epidemic despite near-perfect adherence to mainstream dietary guidelines. We discuss why LDL and cholesterol are the wrong targets, the silent crisis of undiagnosed diabetes in young adults, how even "omnivores" are undernourished in meat-deficient diets, and why emergency doctors may be the last line of defense in failed systems. This is a video for anyone who suspects that nutrition science, as we've been told, is broken, and wants to hear what frontline data is starting to show us. Watch until the end for insight on where this research is headed and how you can follow the results when they're published!
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Summary
Dr. Ankor, an emergency medical physician in India and host of the Desi EM podcast, discusses his ongoing research exploring the relationship between diet, metabolic syndromes, and cardiovascular health in the Indian population. His studies focus on observational epidemiological data collected from over 10,000 patients in emergency settings, investigating dietary patterns—especially pbf versus omnivorous or carnivore diets—and their association with diseases such as diabetes, heart disease, hypertension, PCOS, and metabolic dysfunction-related liver disease. Dr. Ankor highlights the paradox that many patients adhering to traditional Indian pbf diets still suffer from high rates of metabolic diseases, challenging the widely held assumption that pbf diets are inherently protective.
A significant finding from his research is the widespread vitamin B12 deficiency and elevated homocysteine levels among patients, which correlate strongly with heart attacks and arrhythmias despite normal cholesterol profiles. This challenges the conventional focus on cholesterol as the main culprit in cardiovascular disease. Dr. Ankor emphasizes the importance of nutrition beyond the standard dietary guidelines followed by most Indians, which include cereals, lentils, vegetables, and limited meat intake. He advocates for more nuanced understanding of nutrition’s role in metabolic health and encourages a carnivore or animal-product-inclusive approach for some patients, especially those with nutrient deficiencies like B12.
He also discusses the difficulties in changing dietary habits, noting fear of change and cultural beliefs as major barriers, alongside sugar addiction. His studies aim to provide clearer evidence on the associations between diet, metabolic markers, and chronic disease outcomes, with planned publications expected through emergency medicine and nutrition journals by 2026. Dr. Ankor’s work highlights the limitations of current dietary guidelines and the need for a patient-centered, metabolism-focused approach to prevent and manage chronic diseases.
Highlights
- 🩺 Dr. Ankor conducts large-scale observational studies in emergency medicine focusing on diet and metabolic diseases in India.
- 🥦 Despite a predominantly pbf population, India faces a high burden of diabetes and heart disease, challenging assumptions about pbf diets.
- 🧬 Elevated homocysteine and vitamin B12 deficiency are strongly associated with heart attacks and arrhythmias, independent of cholesterol levels.
- 🍖 Most "omnivores" in the Indian context consume meat very infrequently, often once a week or less.
- 🍚 Traditional Indian dietary guidelines emphasizing grains, legumes, and vegetables are widely followed but may not prevent metabolic syndrome.
- 💉 Supplementation of vitamin B12 shows promise in reducing homocysteine and managing metabolic health, but full clinical adoption and follow-up remain challenges.
- 📅 Multiple studies are underway with data collection concluding in 2026, aiming to publish in emergency medicine and nutrition journals to influence clinical practice.
Key Insights
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🏥 Emergency Medicine as a Unique Research Setting: Dr. Ankor leverages emergency department encounters to study chronic metabolic diseases, a novel approach since emergency medicine traditionally focuses on acute care. This setting provides a large, diverse patient population with metabolic complications, offering valuable real-world data on disease presentation and management gaps. The emergency department acts as a frontline for observing the consequences of chronic dietary and metabolic issues.
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🍛 PBF Diets and Metabolic Disease in India: The high prevalence of diabetes and cardiovascular disease in a largely PBF population suggests that PBF alone is not protective. This contradicts many Western dietary assumptions and underscores the complexity of nutrition, genetics, and lifestyle in disease etiology. The quality of PBF diets, potential micronutrient deficiencies (especially B12), and carbohydrate-heavy staples likely contribute to disease risk.
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🧪 Vitamin B12 and Homocysteine as Critical Markers: Elevated homocysteine, a procoagulant amino acid, and deficient B12 levels emerge as significant correlates with heart attacks and arrhythmias. These findings challenge the traditional focus on cholesterol and LDL as prime targets, suggesting that metabolic and nutritional deficiencies play a major role in cardiovascular risk. This insight calls for broader diagnostic panels and therapeutic approaches targeting nutrient status and homocysteine reduction.
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🍖 Limited Meat Consumption Among Self-Identified Omnivores: In India, omnivores often consume meat only once or twice weekly, which may be insufficient to meet B12 needs. This highlights how dietary categories can mask nutritional deficiencies and the need to quantify actual intake rather than rely on broad labels. It also explains why “meat-eaters” in India may still suffer from nutrient deficiencies assumed to be exclusive to PBF followers.
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🍚 Dietary Guidelines vs. Real-World Outcomes: Despite high adherence to official dietary guidelines emphasizing whole grains, lentils, vegetables, and minimal animal products, metabolic diseases remain rampant. This discrepancy points to limitations in current guidelines that fail to address individual metabolic needs, micronutrient sufficiency, and the impact of refined carbohydrates and sugar addiction prevalent in Indian diets. It also reflects the complexity of metabolic diseases, which involve multiple lifestyle and environmental factors beyond diet alone.
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📉 Challenges in Patient Compliance and Behavior Change: Only a minority (~10-20%) of patients follow dietary recommendations or switch to carnivore or low-carb approaches despite educational efforts. Fear of change, cultural beliefs, and addictive properties of sugar and staple foods like rice impede adherence. This underscores the importance of patient-centric counseling, gradual transitions, and addressing behavioral and psychological barriers in clinical nutrition interventions.
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📊 Robust Statistical Analysis to Isolate Dietary Effects: Dr. Ankor plans extensive regression analyses controlling for smoking, alcohol, exercise, and other confounders to clarify independent associations between diet and metabolic outcomes. This rigorous approach will help disentangle complex multifactorial influences and provide clearer evidence to guide clinical practice. The large sample size (~10,000 patients) enhances the power to detect meaningful associations and challenge existing paradigms in nutrition science.
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🩺 Implications for Global Nutrition and Cardiovascular Guidelines: The Indian context, with its unique dietary patterns and disease burden, offers critical insights that may apply globally. The data challenge the generalized vilification of animal fat and meat in cardiovascular disease and highlight the need to reconsider nutrient deficiencies, carbohydrate quality, and metabolic markers beyond cholesterol. This could lead to more individualized, culturally tailored dietary guidelines worldwide.
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🔬 Need for Open Publication and Knowledge Dissemination: Dr. Ankor aims to publish in accessible emergency medicine and nutrition journals indexed on PubMed to maximize reach among clinicians and researchers. Open access and transparency in data sharing will be crucial to overcoming entrenched dogmas in medicine and nutrition and to fostering evidence-based dietary recommendations focused on metabolic health.
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💡 Holistic View of Metabolic Syndrome: The studies incorporate factors beyond diet, including smoking, exercise, alcohol use, and stress, recognizing metabolic syndrome as multifactorial. This comprehensive approach aligns with contemporary understanding that no single dietary factor alone drives disease, but rather the interplay of lifestyle, environment, and genetics.
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🤝 Potential for Clinical Impact and Prevention: By identifying modifiable nutritional deficiencies like B12 and elevated homocysteine as key contributors, these studies offer tangible targets for prevention and treatment. Supplementation and dietary adjustments could reduce recurrent heart attacks, improve metabolic control in diabetes, and enhance overall patient outcomes, reducing emergency visits and healthcare burden.
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🔄 Dynamic Research Pipeline: With multiple studies ongoing and some preliminary case series published, this body of research promises to continuously inform and update clinical practice over the next few years, bridging gaps between emergency medicine, nutrition science, and chronic disease management.
Conclusion
Dr. Ankor’s research represents a pioneering effort to understand the complex relationship between traditional Indian diets, metabolic health, and cardiovascular disease through the lens of emergency medicine. His findings question common nutritional dogmas, highlight critical roles for vitamin B12 and homocysteine, and emphasize the limitations of current dietary guidelines. By combining large-scale epidemiological data, clinical insight, and patient-centered approaches, this work has the potential to reshape nutrition recommendations and improve outcomes for millions living with metabolic diseases in India and beyond.