(Cross posted from https://hackertalks.com/post/5831777/6189597)

Ohh a paper by Norwitz, and Feldman... you know it will be nuanced!

FYI I can't remove the chronic downvoters on lemmy.world, but the !carnivore@lemm.ee has automation to remove anyone who only participates negatively

Conclusions: These data suggest that, in contrast to the typical pattern of dyslipidemia, greater LDL cholesterol elevation on a CRD tends to occur in the context of otherwise low cardiometabolic risk.

It is interesting how the LDL hyper responders don't have metabolic syndrome!

Really nice to see the raw data published to github! This should be the standard for research

Observational study with online questionnaires, so this is lower on the evidence pyramid, but a good place to generate hypothesis and do stronger science from.

I need to do a writeup of these referenced papers

19. Boizel R, Benhamou PY, Lardy B, Laporte F, Foulon T, Halimi S. Ratio of triglycerides to HDL cholesterol is an indicator of LDL particle size in patients with type 2 diabetes and normal HDL cholesterol levels. Diabetes Care 2000;23(11):1679–85.

20. Moriyama K. The association between the triglyceride to high-density lipoprotein cholesterol ratio and low-density lipoprotein subclasses. Intern Med 2020;59(21):2661–9.

I should just add, generally, the "bad" cholesterol is actually damaged cholesterol.

glycated and oxidized LDL doesn't get absorbed by the liver, and thus can be seen as spike in LDL levels. High LDL isn't bad for you, Damaged LDL is bad for you.

Thankfully you don't have to spend a bunch of money to centrifuge the LDL sample, you can just check your TG/HDL ratio to see if your insulin sensitive, and if you are, the LDL isn't damaged (to a high degree of correlative probability)

You might also find this paper interesting: https://hackertalks.com/post/6008675

TLDR: Cholesterol is good for you, as long as it isn't damaged

Ban me too since Vegan Pizza called you out on your nonsense.