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the effects of psilocybin can be dampened by SSRI/SNRI for up to 3 months after cessation (pure.johnshopkins.edu)

submitted 7 months ago by pelletbucket@lemm.ee to c/drugs@lemmy.ml

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paper from Johns Hopkins. I wouldn't say the numbers are rock solid, but it's better than anecdotal

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[–] breadsmasher@lemmy.world 5 points 7 months ago (1 children)

Methods: Online retrospective survey of individuals with use of psilocybin mushrooms (1) with an antidepressant and/or (2) within 2 years of discontinuing an antidepressant. Participants who took mushrooms with an antidepressant and either took the same dose pre-antidepressant or took the same dose with other people not on antidepressant reported the strength of drug effects relative to their expectation. Participants who took mushrooms following discontinuation of an antidepressant also reported the presence of weakened effects.

Am I understanding the abstract here correctly - the only method used was an online survey?

[–] scrion@lemmy.world 2 points 7 months ago (1 children)

Yes, that seems to be the case indeed.

[–] Randomgal@lemmy.ca 3 points 7 months ago (1 children)

So it's BARELY better than anecdotal. (Literally a collection of anecdotes)

[–] scrion@lemmy.world 1 points 7 months ago

Yes, I would absolutely agree. There are so many factors affecting memory / recall that I'm wondering why self-reported surveys are still used at all - I get they're simple and comparatively cheap to setup, but I would have assumed research into the therapeutic use of psychedelics has progressed far enough for somebody to cough up money for a more elaborate setup.