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Adblockers stop publishers serving ads to (or even seeing) 1bn web users - Press Gazette
(pressgazette.co.uk)
This is a most excellent place for technology news and articles.
I don’t know if anyone reading this will ever have this problem (if you got this far without installing an adblocker, this is your wake up call - go get one now), but ctrl+W is the shortcut to kill a tab and that should work regardless site focus or popups
Unless the lovely javascript detects that you're trying to close the tab and hijacks that to ask you if you are sure you want to ~~forcefully tell them to fuck off and die~~ leave the page. It's only one extra click, sure, but I remember some from the old days that wouldn't let you close shit. Ugh, thank god for better modern standards and adblockers.