"Yes", for any bits the user sees. The frontend UI can be behind Anubis without issues. The API, including both user and federation, cannot. We expect "bots" to use an API, so you can't put human verification in front of it. These "bots* also include applications that aren't aware of Anubis, or unable to pass it, like all third party Lemmy apps.

That does stop almost all generic AI scraping, though it does not prevent targeted abuse.