For me it's Corner Gas. I still think it's pretty funny and there's a decent amount of references to Canadian stuff but not enough to be off-putting. I feel like an American wouldn't be confused watching it even if some of the references get a bit dated overtime.
I have only seen a bit of the animated version in waiting rooms.
King of Kensington, Adventures in Rainbow Country, Smith and Smith, All Around the Circle, The Irish Rovers Show, The Wolfman Jack Show, Front Page Challenge, This Is the Law, The Beachcombers, The Friendly Giant, The Littlest Hobo, Mr. Dressup